FOXO3 anticorps (C-Term)

N° du produit ABIN2780367

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXO3 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Mouton, Cheval, Lapin et Cobaye.

Aperçu rapide pour FOXO3 anticorps (C-Term) (ABIN2780367)

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Mouton, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FOXO3 anticorps

Épitope: C-Term

Séquence: MESIIRSELM DADGLDFNFD SLISTQNVVG LNVGNFTGAK QASSQSWVPG

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FOXO3A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human FOXO3A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 453 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FOXO3

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Autre désignation: FOXO3A

Sujet: FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.
Alias Symbols: FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2
Protein Interaction Partner: SMAD3, YWHAB, ERBB2IP, SIRT1, YWHAE, CDK6, AKT1, IKBKB, CHUK, CDT1, UBC, SKP2, MAPK1, PCNA, MDM2, BTRC, CREBBP, ELAVL1, SMAD4, MAPK6, NR1H3, NR1H2, NLK, VDR, SMAD1, EP300, STK4, FANCD2, RAD17, MYC, H2AFX, BRCA1, ATM, SIRT3, ATG101, YWHAH, PGK1, GBAS, FKBP
Protein Size: 453

Poids moléculaire: 50 kDa

ID gène: 2309

NCBI Accession: NM_001455

UniProt: Q68DV3

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis